{"id":662,"date":"2026-03-15T06:05:53","date_gmt":"2026-03-15T04:05:53","guid":{"rendered":"https:\/\/hala-care.com\/articles\/scientists-discover-als-protein-that-links-dna-repair-to-cancer-and-dementia\/"},"modified":"2026-03-15T06:05:53","modified_gmt":"2026-03-15T04:05:53","slug":"scientists-discover-als-protein-that-links-dna-repair-to-cancer-and-dementia","status":"publish","type":"post","link":"https:\/\/hala-care.com\/articles\/scientists-discover-als-protein-that-links-dna-repair-to-cancer-and-dementia\/","title":{"rendered":"Scientists discover ALS protein that links DNA repair to cancer and dementia"},"content":{"rendered":"<p>A protein tied to ALS and dementia may have a much bigger role in disease than scientists realized. Researchers found that TDP43 controls a key DNA repair process, but when the protein becomes imbalanced, the repair system can spiral out of control, harming neurons and destabilizing DNA. The team also discovered that high levels of the protein are linked to increased mutation rates in cancer. The discovery places TDP43 at the center of both neurodegeneration and cancer biology.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>A protein tied to ALS and dementia may have a much bigger role in disease than scientists realized. Researchers found that TDP43 controls a key&#8230;<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[],"class_list":["post-662","post","type-post","status-publish","format-standard","hentry","category-blog"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v26.2 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Scientists discover ALS protein that links DNA repair to cancer and dementia - \u0645\u0643\u062a\u0628\u0629 \u0647\u0644\u0627 \u0643\u064a\u0631 \u0627\u0644\u0637\u0628\u064a\u0629<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/hala-care.com\/articles\/scientists-discover-als-protein-that-links-dna-repair-to-cancer-and-dementia\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Scientists discover ALS protein that links DNA repair to cancer and dementia - \u0645\u0643\u062a\u0628\u0629 \u0647\u0644\u0627 \u0643\u064a\u0631 \u0627\u0644\u0637\u0628\u064a\u0629\" \/>\n<meta property=\"og:description\" content=\"A protein tied to ALS and dementia may have a much bigger role in disease than scientists realized. Researchers found that TDP43 controls a key...\" \/>\n<meta property=\"og:url\" content=\"https:\/\/hala-care.com\/articles\/scientists-discover-als-protein-that-links-dna-repair-to-cancer-and-dementia\/\" \/>\n<meta property=\"og:site_name\" content=\"\u0645\u0643\u062a\u0628\u0629 \u0647\u0644\u0627 \u0643\u064a\u0631 \u0627\u0644\u0637\u0628\u064a\u0629\" \/>\n<meta property=\"article:published_time\" content=\"2026-03-15T04:05:53+00:00\" \/>\n<meta name=\"author\" content=\"abdelghany1191\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"abdelghany1191\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\/\/hala-care.com\/articles\/scientists-discover-als-protein-that-links-dna-repair-to-cancer-and-dementia\/\",\"url\":\"https:\/\/hala-care.com\/articles\/scientists-discover-als-protein-that-links-dna-repair-to-cancer-and-dementia\/\",\"name\":\"Scientists discover ALS protein that links DNA repair to cancer and dementia - \u0645\u0643\u062a\u0628\u0629 \u0647\u0644\u0627 \u0643\u064a\u0631 \u0627\u0644\u0637\u0628\u064a\u0629\",\"isPartOf\":{\"@id\":\"https:\/\/hala-care.com\/articles\/#website\"},\"datePublished\":\"2026-03-15T04:05:53+00:00\",\"author\":{\"@id\":\"https:\/\/hala-care.com\/articles\/#\/schema\/person\/e4d08bd5eb82a6f0d6a868794ba2c82e\"},\"breadcrumb\":{\"@id\":\"https:\/\/hala-care.com\/articles\/scientists-discover-als-protein-that-links-dna-repair-to-cancer-and-dementia\/#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/hala-care.com\/articles\/scientists-discover-als-protein-that-links-dna-repair-to-cancer-and-dementia\/\"]}]},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\/\/hala-care.com\/articles\/scientists-discover-als-protein-that-links-dna-repair-to-cancer-and-dementia\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\/\/hala-care.com\/articles\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Scientists discover ALS protein that links DNA repair to cancer and dementia\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\/\/hala-care.com\/articles\/#website\",\"url\":\"https:\/\/hala-care.com\/articles\/\",\"name\":\"\u0645\u0643\u062a\u0628\u0629 \u0647\u0644\u0627 \u0643\u064a\u0631 \u0627\u0644\u0637\u0628\u064a\u0629\",\"description\":\"\u0623\u0643\u062b\u0631 \u0645\u0646 10,000 \u0645\u0642\u0627\u0644 \u0637\u0628\u064a \u0645\u062a\u062e\u0635\u0635\",\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/hala-care.com\/articles\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"en-US\"},{\"@type\":\"Person\",\"@id\":\"https:\/\/hala-care.com\/articles\/#\/schema\/person\/e4d08bd5eb82a6f0d6a868794ba2c82e\",\"name\":\"abdelghany1191\",\"image\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\/\/hala-care.com\/articles\/#\/schema\/person\/image\/\",\"url\":\"https:\/\/secure.gravatar.com\/avatar\/ed77ddfef8dc7d2976ef35085ac6560537fa070e324fb278e56ca13b7016de34?s=96&d=mm&r=g\",\"contentUrl\":\"https:\/\/secure.gravatar.com\/avatar\/ed77ddfef8dc7d2976ef35085ac6560537fa070e324fb278e56ca13b7016de34?s=96&d=mm&r=g\",\"caption\":\"abdelghany1191\"},\"sameAs\":[\"https:\/\/hala-care.com\"],\"url\":\"https:\/\/hala-care.com\/articles\/author\/abdelghany1191\/\"}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Scientists discover ALS protein that links DNA repair to cancer and dementia - \u0645\u0643\u062a\u0628\u0629 \u0647\u0644\u0627 \u0643\u064a\u0631 \u0627\u0644\u0637\u0628\u064a\u0629","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/hala-care.com\/articles\/scientists-discover-als-protein-that-links-dna-repair-to-cancer-and-dementia\/","og_locale":"en_US","og_type":"article","og_title":"Scientists discover ALS protein that links DNA repair to cancer and dementia - \u0645\u0643\u062a\u0628\u0629 \u0647\u0644\u0627 \u0643\u064a\u0631 \u0627\u0644\u0637\u0628\u064a\u0629","og_description":"A protein tied to ALS and dementia may have a much bigger role in disease than scientists realized. 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