{"id":610,"date":"2026-03-03T18:33:04","date_gmt":"2026-03-03T16:33:04","guid":{"rendered":"https:\/\/hala-care.com\/articles\/scientists-find-the-genetic-switch-that-makes-pancreatic-cancer-resist-chemotherapy\/"},"modified":"2026-03-03T18:33:04","modified_gmt":"2026-03-03T16:33:04","slug":"scientists-find-the-genetic-switch-that-makes-pancreatic-cancer-resist-chemotherapy","status":"publish","type":"post","link":"https:\/\/hala-care.com\/articles\/scientists-find-the-genetic-switch-that-makes-pancreatic-cancer-resist-chemotherapy\/","title":{"rendered":"Scientists find the genetic switch that makes pancreatic cancer resist chemotherapy"},"content":{"rendered":"

Scientists have identified a crucial molecular switch that decides whether pancreatic cancer cells resist chemotherapy or respond to it. The key player, a gene called GATA6, keeps tumours in a more structured and treatable form\u2014but it gets shut down by an overactive KRAS-driven pathway. When researchers blocked that pathway, GATA6 levels rebounded and cancer cells became more sensitive to chemo. The discovery could help turn some of the toughest pancreatic tumours into ones doctors can better control.<\/p>\n","protected":false},"excerpt":{"rendered":"

Scientists have identified a crucial molecular switch that decides whether pancreatic cancer cells resist chemotherapy or respond to it. The key player, a gene called…<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[],"class_list":["post-610","post","type-post","status-publish","format-standard","hentry","category-blog"],"yoast_head":"\nScientists find the genetic switch that makes pancreatic cancer resist chemotherapy - \u0645\u0643\u062a\u0628\u0629 \u0647\u0644\u0627 \u0643\u064a\u0631 \u0627\u0644\u0637\u0628\u064a\u0629<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/hala-care.com\/articles\/scientists-find-the-genetic-switch-that-makes-pancreatic-cancer-resist-chemotherapy\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Scientists find the genetic switch that makes pancreatic cancer resist chemotherapy - \u0645\u0643\u062a\u0628\u0629 \u0647\u0644\u0627 \u0643\u064a\u0631 \u0627\u0644\u0637\u0628\u064a\u0629\" \/>\n<meta property=\"og:description\" content=\"Scientists have identified a crucial molecular switch that decides whether pancreatic cancer cells resist chemotherapy or respond to it. 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