{"id":1120,"date":"2026-07-04T22:26:54","date_gmt":"2026-07-04T19:26:54","guid":{"rendered":"https:\/\/hala-care.com\/articles\/a-hidden-weakness-in-deadly-cancers-could-lead-to-powerful-new-treatments\/"},"modified":"2026-07-04T22:26:54","modified_gmt":"2026-07-04T19:26:54","slug":"a-hidden-weakness-in-deadly-cancers-could-lead-to-powerful-new-treatments","status":"publish","type":"post","link":"https:\/\/hala-care.com\/articles\/a-hidden-weakness-in-deadly-cancers-could-lead-to-powerful-new-treatments\/","title":{"rendered":"A hidden weakness in deadly cancers could lead to powerful new treatments"},"content":{"rendered":"

A UCLA study has identified a hidden Achilles’ heel in aggressive small cell cancers that have resisted new treatments for decades. Scientists found that tumors lacking the RB gene become critically dependent on the protein E2F3 for survival. Blocking E2F3 shut down tumor growth in laboratory models, and existing FDA-approved drugs may be able to exploit this vulnerability. The discovery could pave the way for faster development of more effective therapies.<\/p>\n","protected":false},"excerpt":{"rendered":"

A UCLA study has identified a hidden Achilles’ heel in aggressive small cell cancers that have resisted new treatments for decades. Scientists found that tumors…<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[],"class_list":["post-1120","post","type-post","status-publish","format-standard","hentry","category-blog"],"yoast_head":"\nA hidden weakness in deadly cancers could lead to powerful new treatments - \u0645\u0643\u062a\u0628\u0629 \u0647\u0644\u0627 \u0643\u064a\u0631 \u0627\u0644\u0637\u0628\u064a\u0629<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/hala-care.com\/articles\/a-hidden-weakness-in-deadly-cancers-could-lead-to-powerful-new-treatments\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"A hidden weakness in deadly cancers could lead to powerful new treatments - \u0645\u0643\u062a\u0628\u0629 \u0647\u0644\u0627 \u0643\u064a\u0631 \u0627\u0644\u0637\u0628\u064a\u0629\" \/>\n<meta property=\"og:description\" content=\"A UCLA study has identified a hidden Achilles’ heel in aggressive small cell cancers that have resisted new treatments for decades. Scientists found that tumors...\" \/>\n<meta property=\"og:url\" content=\"https:\/\/hala-care.com\/articles\/a-hidden-weakness-in-deadly-cancers-could-lead-to-powerful-new-treatments\/\" \/>\n<meta property=\"og:site_name\" content=\"\u0645\u0643\u062a\u0628\u0629 \u0647\u0644\u0627 \u0643\u064a\u0631 \u0627\u0644\u0637\u0628\u064a\u0629\" \/>\n<meta property=\"article:published_time\" content=\"2026-07-04T19:26:54+00:00\" \/>\n<meta name=\"author\" content=\"abdelghany1191\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"abdelghany1191\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\/\/hala-care.com\/articles\/a-hidden-weakness-in-deadly-cancers-could-lead-to-powerful-new-treatments\/\",\"url\":\"https:\/\/hala-care.com\/articles\/a-hidden-weakness-in-deadly-cancers-could-lead-to-powerful-new-treatments\/\",\"name\":\"A hidden weakness in deadly cancers could lead to powerful new treatments - \u0645\u0643\u062a\u0628\u0629 \u0647\u0644\u0627 \u0643\u064a\u0631 \u0627\u0644\u0637\u0628\u064a\u0629\",\"isPartOf\":{\"@id\":\"https:\/\/hala-care.com\/articles\/#website\"},\"datePublished\":\"2026-07-04T19:26:54+00:00\",\"author\":{\"@id\":\"https:\/\/hala-care.com\/articles\/#\/schema\/person\/e4d08bd5eb82a6f0d6a868794ba2c82e\"},\"breadcrumb\":{\"@id\":\"https:\/\/hala-care.com\/articles\/a-hidden-weakness-in-deadly-cancers-could-lead-to-powerful-new-treatments\/#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/hala-care.com\/articles\/a-hidden-weakness-in-deadly-cancers-could-lead-to-powerful-new-treatments\/\"]}]},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\/\/hala-care.com\/articles\/a-hidden-weakness-in-deadly-cancers-could-lead-to-powerful-new-treatments\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\/\/hala-care.com\/articles\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"A hidden weakness in deadly cancers could lead to powerful new treatments\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\/\/hala-care.com\/articles\/#website\",\"url\":\"https:\/\/hala-care.com\/articles\/\",\"name\":\"\u0645\u0643\u062a\u0628\u0629 \u0647\u0644\u0627 \u0643\u064a\u0631 \u0627\u0644\u0637\u0628\u064a\u0629\",\"description\":\"\u0623\u0643\u062b\u0631 \u0645\u0646 10,000 \u0645\u0642\u0627\u0644 \u0637\u0628\u064a \u0645\u062a\u062e\u0635\u0635\",\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/hala-care.com\/articles\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"en-US\"},{\"@type\":\"Person\",\"@id\":\"https:\/\/hala-care.com\/articles\/#\/schema\/person\/e4d08bd5eb82a6f0d6a868794ba2c82e\",\"name\":\"abdelghany1191\",\"image\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\/\/hala-care.com\/articles\/#\/schema\/person\/image\/\",\"url\":\"https:\/\/secure.gravatar.com\/avatar\/ed77ddfef8dc7d2976ef35085ac6560537fa070e324fb278e56ca13b7016de34?s=96&d=mm&r=g\",\"contentUrl\":\"https:\/\/secure.gravatar.com\/avatar\/ed77ddfef8dc7d2976ef35085ac6560537fa070e324fb278e56ca13b7016de34?s=96&d=mm&r=g\",\"caption\":\"abdelghany1191\"},\"sameAs\":[\"https:\/\/hala-care.com\"],\"url\":\"https:\/\/hala-care.com\/articles\/author\/abdelghany1191\/\"}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"A hidden weakness in deadly cancers could lead to powerful new treatments - \u0645\u0643\u062a\u0628\u0629 \u0647\u0644\u0627 \u0643\u064a\u0631 \u0627\u0644\u0637\u0628\u064a\u0629","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/hala-care.com\/articles\/a-hidden-weakness-in-deadly-cancers-could-lead-to-powerful-new-treatments\/","og_locale":"en_US","og_type":"article","og_title":"A hidden weakness in deadly cancers could lead to powerful new treatments - \u0645\u0643\u062a\u0628\u0629 \u0647\u0644\u0627 \u0643\u064a\u0631 \u0627\u0644\u0637\u0628\u064a\u0629","og_description":"A UCLA study has identified a hidden Achilles’ heel in aggressive small cell cancers that have resisted new treatments for decades. Scientists found that tumors...","og_url":"https:\/\/hala-care.com\/articles\/a-hidden-weakness-in-deadly-cancers-could-lead-to-powerful-new-treatments\/","og_site_name":"\u0645\u0643\u062a\u0628\u0629 \u0647\u0644\u0627 \u0643\u064a\u0631 \u0627\u0644\u0637\u0628\u064a\u0629","article_published_time":"2026-07-04T19:26:54+00:00","author":"abdelghany1191","twitter_card":"summary_large_image","twitter_misc":{"Written by":"abdelghany1191"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"WebPage","@id":"https:\/\/hala-care.com\/articles\/a-hidden-weakness-in-deadly-cancers-could-lead-to-powerful-new-treatments\/","url":"https:\/\/hala-care.com\/articles\/a-hidden-weakness-in-deadly-cancers-could-lead-to-powerful-new-treatments\/","name":"A hidden weakness in deadly cancers could lead to powerful new treatments - \u0645\u0643\u062a\u0628\u0629 \u0647\u0644\u0627 \u0643\u064a\u0631 \u0627\u0644\u0637\u0628\u064a\u0629","isPartOf":{"@id":"https:\/\/hala-care.com\/articles\/#website"},"datePublished":"2026-07-04T19:26:54+00:00","author":{"@id":"https:\/\/hala-care.com\/articles\/#\/schema\/person\/e4d08bd5eb82a6f0d6a868794ba2c82e"},"breadcrumb":{"@id":"https:\/\/hala-care.com\/articles\/a-hidden-weakness-in-deadly-cancers-could-lead-to-powerful-new-treatments\/#breadcrumb"},"inLanguage":"en-US","potentialAction":[{"@type":"ReadAction","target":["https:\/\/hala-care.com\/articles\/a-hidden-weakness-in-deadly-cancers-could-lead-to-powerful-new-treatments\/"]}]},{"@type":"BreadcrumbList","@id":"https:\/\/hala-care.com\/articles\/a-hidden-weakness-in-deadly-cancers-could-lead-to-powerful-new-treatments\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https:\/\/hala-care.com\/articles\/"},{"@type":"ListItem","position":2,"name":"A hidden weakness in deadly cancers could lead to powerful new treatments"}]},{"@type":"WebSite","@id":"https:\/\/hala-care.com\/articles\/#website","url":"https:\/\/hala-care.com\/articles\/","name":"\u0645\u0643\u062a\u0628\u0629 \u0647\u0644\u0627 \u0643\u064a\u0631 \u0627\u0644\u0637\u0628\u064a\u0629","description":"\u0623\u0643\u062b\u0631 \u0645\u0646 10,000 \u0645\u0642\u0627\u0644 \u0637\u0628\u064a \u0645\u062a\u062e\u0635\u0635","potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/hala-care.com\/articles\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"en-US"},{"@type":"Person","@id":"https:\/\/hala-care.com\/articles\/#\/schema\/person\/e4d08bd5eb82a6f0d6a868794ba2c82e","name":"abdelghany1191","image":{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/hala-care.com\/articles\/#\/schema\/person\/image\/","url":"https:\/\/secure.gravatar.com\/avatar\/ed77ddfef8dc7d2976ef35085ac6560537fa070e324fb278e56ca13b7016de34?s=96&d=mm&r=g","contentUrl":"https:\/\/secure.gravatar.com\/avatar\/ed77ddfef8dc7d2976ef35085ac6560537fa070e324fb278e56ca13b7016de34?s=96&d=mm&r=g","caption":"abdelghany1191"},"sameAs":["https:\/\/hala-care.com"],"url":"https:\/\/hala-care.com\/articles\/author\/abdelghany1191\/"}]}},"_links":{"self":[{"href":"https:\/\/hala-care.com\/articles\/wp-json\/wp\/v2\/posts\/1120","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/hala-care.com\/articles\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/hala-care.com\/articles\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/hala-care.com\/articles\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/hala-care.com\/articles\/wp-json\/wp\/v2\/comments?post=1120"}],"version-history":[{"count":0,"href":"https:\/\/hala-care.com\/articles\/wp-json\/wp\/v2\/posts\/1120\/revisions"}],"wp:attachment":[{"href":"https:\/\/hala-care.com\/articles\/wp-json\/wp\/v2\/media?parent=1120"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/hala-care.com\/articles\/wp-json\/wp\/v2\/categories?post=1120"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/hala-care.com\/articles\/wp-json\/wp\/v2\/tags?post=1120"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}